Find the Cheapest Flights from Santo Domingo to Panama

Unlock the cheapest flights and the best airfares from Santo Domingo to Panama. Make your dream trip both memorable and affordable!

Sun, Nov 23SDQ-PTY
American Airlines

oneway$353

Sun, Nov 23SDQ-PTY
Copa Airlines

oneway$405

Sun, Nov 23SDQ-PTY
Aeromexico

oneway$515

Thu, Apr 3SDQ-PTY
Avianca

oneway$630

Sun, Nov 23SDQ-PTY
Avianca

oneway$633

Thu, Apr 3SDQ-PTY
American Airlines

oneway$709

Thu, Apr 3SDQ-PTY
Copa Airlines

oneway$748

Sun, Nov 23SDQ-PTY
United Airlines

oneway$880

Sun, Nov 23SDQ-PTY
Delta Air Lines

oneway$1,325

Thu, Apr 3SDQ-PTY
Delta Air Lines

oneway$1,368

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Santo Domingo to Panama: Flight information

Cheapest flight found$748

Cheapest month to flyApril

Most popular airlineCopa Airlines

Flights per week1

Popular Airlines flying from
Santo Domingo to Panama

from	to	Fare Type	Departure	Price

Cheapest flight found

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Dec 2024

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Apr 2024

$490

Jan 2024

$513

May 2024

$544

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